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1

Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair

Berkovich, Elijahu, Monnat, Raymond J., Kastan, Michael B.

Journal:

Nature Cell Biology

Year:

2007

Language:

english

File:

PDF, 2.63 MB

english, 2007

2

Human smooth muscle α-actin gene is a transcriptional target of the p53 tumor suppressor protein

Comer, Katherine A, Dennis, Phillip A, Armstrong, Lydia, Catino, Joseph J, Kastan, Michael B, Kumar, C Chandra

Journal:

Year:

1998

Language:

english

File:

PDF, 1.11 MB

english, 1998

3

The DNA Damage Response: Implications for Tumor Responses to Radiation and Chemotherapy

Goldstein, Michael, Kastan, Michael B.

Journal:

Annual Review of Medicine

Year:

2015

Language:

english

File:

PDF, 711 KB

english, 2015

4

Optimization of a Novel Series of Ataxia-Telangiectasia Mutated (ATM) Kinase Inhibitors as Potential Radiosensitizing Agents

Min, Jaeki, Guo, Kexiao, Suryadevara, Praveen K., Zhu, Fangyi, Holbrook, Gloria, Chen, Yizhe, Feau, Clementine, Young, Brandon M, Lemoff, Andrew, Connelly, Michele C., Kastan, Michael B., Guy, R. Kipl

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 2.69 MB

english, 2015

5

Low dose chloroquine decreases insulin resistance in human metabolic syndrome but does not reduce carotid intima-media thickness

McGill, Janet B., Johnson, Mariko, Hurst, Stacy, Cade, William T., Yarasheski, Kevin E., Ostlund, Richard E., Schechtman, Kenneth B., Razani, Babak, Kastan, Michael B., McClain, Donald A., de las Fuen

Journal:

Diabetology and Metabolic Syndrome

Year:

2019

Language:

english

File:

PDF, 1.82 MB

english, 2019

6

Acute neurotoxicity after intrathecal cytosine arabinoside in two adolescents with acute lymphoblastic leukemia of B-cell type

Linda M. S. Resar, Peter C. Phillips, Michael B. Kastan, Brigid G. Leventhal, Paul W. Bowman, Curt I. Civin

Journal:

Year:

1993

Language:

english

File:

PDF, 730 KB

english, 1993

7

Signalling to p53: where does it all start?

Michael B. Kastan

Journal:

Year:

1996

Language:

english

File:

PDF, 342 KB

english, 1996

8

Deficient innate immunity, thymopoiesis, and gene expression response to radiation in survivors of childhood acute lymphoblastic leukemia

Wing Leung, Geoffrey Neale, Fred Behm, Rekha Iyengar, David Finkelstein, Michael B. Kastan, Ching-Hon Pui

Journal:

Cancer Epidemiology

Year:

2010

Language:

english

File:

PDF, 357 KB

english, 2010

9

The NLRP3 Inflammasome Protects against Loss of Epithelial Integrity and Mortality during Experimental Colitis

Md. Hasan Zaki, Kelli L. Boyd, Peter Vogel, Michael B. Kastan, Mohamed Lamkanfi, Thirumala-Devi Kanneganti

Journal:

Year:

2010

Language:

english

File:

PDF, 1.71 MB

english, 2010

10

P53, cell cycle control and apoptosis: Implications for cancer

Michael B. Kastan, Christine E. Canman, Christopher J. Leonard

Journal:

Cancer and Metastasis Reviews

Year:

1995

Language:

english

File:

PDF, 1.20 MB

english, 1995

11

Versicherungsrechtliche Medizin

Hiller, Romanese, K. Löwenstein, Kurt Mendel, Kastan, Antoreferat, S. Kalischer, Michael, Meggendorfer, F. Stern, Jendralski, M. Friedmann, Friedemann, Heinrich Brieger, Engelhardt, A. Stapf, Kaerger,

Journal:

International Journal of Legal Medicine

Year:

1931

Language:

german

File:

PDF, 787 KB

german, 1931

12

Versicherungsrechtliche Medizin

Hiller, Romanese, K. Löwenstein, Kurt Mendel, Kastan, Autoreferat, S. Kalischer, Michael, Meggendorfer, F. Stern, Jendralski, M. Friedmann, Freidemann, Heinrich Brieger, Engelhardt, A. Stapf, Kaerger,

Journal:

International Journal of Legal Medicine

Year:

1931

Language:

german

File:

PDF, 787 KB

german, 1931

13

Glioblastoma-related gene mutations and over-expression of functional epidermal growth factor receptors in SKMG-3 glioma cells

Christopher Thomas, Greg Ely, David C. James, Robert Jenkins, Michael Kastan, Anne Jedlicka, Peter Burger, Robert Wharen

Journal:

Acta Neuropathologica

Year:

2001

Language:

english

File:

PDF, 302 KB

english, 2001

14

10.1038/35007091

Kastan, Michael B., Lim, Dae-Sik, Kim, Seong-Tae, Xu, Bo, Maser, Richard S., Lin, Junyu, Petrini, John H.J.

Journal:

Year:

2000

Language:

english

File:

PDF, 264 KB

english, 2000

15

10.1038/35030277

Cleveland, John L., Kastan, Michael B.

Journal:

Year:

2000

Language:

english

File:

PDF, 219 KB

english, 2000

16

10.1038/35043058

Kastan, Michael B., Lim, Dae-sik

Journal:

Nature Reviews Molecular Cell Biology

Year:

2000

Language:

english

File:

PDF, 367 KB

english, 2000

17

10.1038/35046542

Kastan, Michael B., Yang, Da-Qing

Journal:

Nature Cell Biology

Year:

2000

Language:

english

File:

PDF, 1.32 MB

english, 2000

18

10.1038/35071218

Kastan, Michael B.

Journal:

Year:

2001

Language:

english

File:

PDF, 125 KB

english, 2001

19

Reversal of apoptosis by the leukaemia-associated E2A–HLF chimaeric transcription factor

Inaba, Toshiya, Inukai, Takeshi, Yoshihara, Takao, Seyschab, Helga, Ashmun, Richard A., Canman, Christine E., Laken, Steven J., Kastan, Michael B., Look, A. Thomas

Journal:

Year:

1996

File:

PDF, 868 KB

1996

20

Three paths to stress relief

Canman, Christine E., Kastan, Michael B.

Journal:

Year:

1996

File:

PDF, 621 KB

1996

21

Cell biology: A BID for the pathway

Kastan, Michael B.

Journal:

Year:

2005

Language:

english

File:

PDF, 249 KB

english, 2005

22

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

Bakkenist, Christopher J., Kastan, Michael B.

Journal:

Year:

2003

Language:

english

File:

PDF, 561 KB

english, 2003

23

Cell-cycle checkpoints and cancer

Kastan, Michael B., Bartek, Jiri

Journal:

Year:

2004

Language:

english

File:

PDF, 702 KB

english, 2004

24

p53: a two-faced cancer gene

Kastan, Michael B., Berkovich, Elijahu

Journal:

Nature Cell Biology

Year:

2007

Language:

english

File:

PDF, 175 KB

english, 2007

25

Interaction of FANCD2 and NBS1 in the DNA damage response

Moreau, Lisa A., Stotsky, Maria, Mathew, Christopher G., Kastan, Michael B., Weaver, David T., D'Andrea, Alan D., Nakanishi, Koji, Taniguchi, Toshiyasu, Ranganathan, Velvizhi, New, Helen V.

Journal:

Nature Cell Biology

Year:

2002

Language:

english

File:

PDF, 1.18 MB

english, 2002

26

On the TRAIL from p53 to apoptosis?

Kastan, Michael

Journal:

Nature Genetics

Year:

1997

File:

PDF, 228 KB

1997

27

Experimental models of human carcinogenesis

Kastan, Michael B.

Journal:

Nature Genetics

Year:

1993

File:

PDF, 196 KB

1993

28

To oxidize or not to oxidize?

Kastan, Michael B.

Journal:

Nature Medicine

Year:

1997

File:

PDF, 276 KB

1997

29

Assessment of protein dynamics and DNA repair following generation of DNA double-strand breaks at defined genomic sites

Berkovich, Elijahu, Monnat, Raymond J, Kastan, Michael B

Journal:

Nature Protocols

Year:

2008

Language:

english

File:

PDF, 189 KB

english, 2008

30

Influence of ATM function on telomere metabolism

Smilenov, Lubomir B, Morgan, Susan E, Sawant, Satin G, Kastan, Michael B, Pandita, Tej K

Journal:

Year:

1997

Language:

english

File:

PDF, 374 KB

english, 1997

31

Small contribution of G1 checkpoint control manipulation to modulation of p53-mediated apoptosis

Canman, Christine E, Kastan, Michael B

Journal:

Year:

1998

Language:

english

File:

PDF, 456 KB

english, 1998

32

Ionizing radiation activates the ATM kinase throughout the cell cycle

Pandita, Tej K, Lieberman, Howard B, Lim, Dae-Sik, Dhar, Sonu, Zheng, Wei, Taya, Yoichi, Kastan, Michael B

Journal:

Year:

2000

Language:

english

File:

PDF, 271 KB

english, 2000

33

Distinct functional domains of Nbs1 modulate the timing and magnitude of ATM activation after low doses of ionizing radiation

Hořejší, Zuzana, Falck, Jacob, Bakkenist, Christopher J, Kastan, Michael B, Lukas, Jiri, Bartek, Jiri

Journal:

Year:

2004

Language:

english

File:

PDF, 207 KB

english, 2004

34

Induction of apoptosis by tumor suppressor genes and oncogenes

Christine E. Canman, Michael B. Kastan

Journal:

Seminars in Cancer Biology

Year:

1995

Language:

english

File:

PDF, 82 KB

english, 1995

35

A subtle t(3;8) results in plausible juxtaposition of MYC and BCL6 in a child with Burkitt lymphoma/leukemia and ataxia-telangiectasia

John T. Sandlund, Michael B. Kastan, Wren Kennedy, Frederick Behm, Elaine Entrekin, Ching-Hon Pui, David T. Kalwinsky, Susana C. Raimondi

Journal:

Cancer Genetics and Cytogenetics

Year:

2006

Language:

english

File:

PDF, 181 KB

english, 2006

36

Multiple roles of ATM in monitoring and maintaining DNA integrity

Frederick A. Derheimer, Michael B. Kastan

Journal:

Year:

2010

Language:

english

File:

PDF, 461 KB

english, 2010

37

Phosphatases join kinases in DNA-damage response pathways

Christopher J Bakkenist, Michael B Kastan

Journal:

Trends in Cell Biology

Year:

2004

Language:

english

File:

PDF, 214 KB

english, 2004

38

Molecular determinants of sensitivity to antitumor agents

Michael B Kastan

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Year:

1999

Language:

english

File:

PDF, 211 KB

english, 1999

39

Our cells get stressed too! Implications for human disease

Michael B. Kastan

Journal:

Blood Cells, Molecules, and Diseases

Year:

2007

Language:

english

File:

PDF, 119 KB

english, 2007

40

Initiating Cellular Stress Responses

Christopher J Bakkenist, Michael B Kastan

Journal:

Year:

2004

Language:

english

File:

PDF, 304 KB

english, 2004

41

Regulation of p53 Translation and Induction after DNA Damage by Ribosomal Protein L26 and Nucleolin

Masatoshi Takagi, Michael J. Absalon, Kevin G. McLure, Michael B. Kastan

Journal:

Year:

2005

Language:

english

File:

PDF, 742 KB

english, 2005

42

Regulation of p53 Translation and Induction after DNA Damage by Ribosomal Protein L26 and Nucleolin

Masatoshi Takagi, Michael J. Absalon, Kevin G. McLure, Michael B. Kastan

Journal:

Year:

2005

Language:

english

File:

PDF, 125 KB

english, 2005

43

Wild-Type p53: Tumors Can't Stand It

Michael B. Kastan

Journal:

Year:

2007

Language:

english

File:

PDF, 235 KB

english, 2007

44

ATM-dependent suppression of stress signaling reduces vascular disease in metabolic syndrome

Jochen G. Schneider, Brian N. Finck, Jie Ren, Kara N. Standley, Masatoshi Takagi, Kirsteen H. Maclean, Carlos Bernal-Mizrachi, Anthony J. Muslin, Michael B. Kastan, Clay F. Semenkovich

Journal:

Cell Metabolism

Year:

2006

Language:

english

File:

PDF, 1.54 MB

english, 2006

45

Autophagy Links Inflammasomes to Atherosclerotic Progression

Babak Razani, Chu Feng, Trey Coleman, Roy Emanuel, Haitao Wen, Seungmin Hwang, Jenny P. Ting, Herbert W. Virgin, Michael B. Kastan, Clay F. Semenkovich

Journal:

Cell Metabolism

Year:

2012

Language:

english

File:

PDF, 1.31 MB

english, 2012

46

Mdm2 Regulates p53 mRNA Translation through Inhibitory Interactions with Ribosomal Protein L26

Yaara Ofir-Rosenfeld, Kristy Boggs, Dan Michael, Michael B. Kastan, Moshe Oren

Journal:

Year:

2008

Language:

english

File:

PDF, 539 KB

english, 2008

47

Convergence of the Fanconi Anemia and Ataxia Telangiectasia Signaling Pathways

Toshiyasu Taniguchi, Irene Garcia-Higuera, Bo Xu, Paul R. Andreassen, Richard C. Gregory, Seong-Tae Kim, William S. Lane, Michael B. Kastan, Alan D. D'Andrea

Journal:

Year:

2002

Language:

english

File:

PDF, 683 KB

english, 2002

48

Parc-ing p53 in the Cytoplasm

Michael B. Kastan, Gerard P. Zambetti

Journal:

Year:

2003

Language:

english

File:

PDF, 81 KB

english, 2003

49

Cellular survival pathways and resistance to cancer therapy

Phillip A. Dennis, Michael B. Kastan

Journal:

Drug Resistance Updates

Year:

1998

Language:

english

File:

PDF, 1.20 MB

english, 1998

50

A new role for ATM

Valentin-Vega, Yasmine A., Kastan, Michael B.

Journal:

Year:

2012

Language:

english

File:

PDF, 143 KB

english, 2012